Today, IBM generously hosted the GSE TWS BeLux 2010 conference. Although it was organized together with the GSE DB2 conference (which I would also have loved to attend) I must say I was pretty impressed with the topics given, especially those after the lunch.
For me, personally, the topic on TWS 8.5.1 with broker functionality was most impressive. Not that the features are extremely innovative, but they are very useful (especially in an enterprise context). I don't know if you have (production) experience with TWS Broker (or even 8.5.1's broker functionality) - if you do, I'd love to hear about it!